Tetrahydro-1,4-thiazine-3,5-dione

Synthesis, characterization and biological studies of some 3,5-diaryl-tetrahydro-N-formyl-1,4-thiazine-1,1-dioxide

A series of some new 3, 5-diaryl-tetrahydro-N-formyl-1, 4-thiazine-1, 1-dioxides has been synthesized from their respective thiazine compounds. The structural assignments are based on their elemental and spectral data. All the synthesized compounds were preliminarily screened for their in vitro antimicrobial activity against Gram positive organisms (Bacillus subtilis, Staphylococcus aureus) and...

Asymmetric synthesis of (7aS)-7a-methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and useful derivatives thereof.

The enantioselective synthesis of the title compound, using Meyers' bicyclic lactam methodology, is described. This compound and a few of its derivatives are useful intermediates in natural product synthesis.

On the oxidation of D-1, 3-thiazane-4-carboxylic acid (D-tetrahydro-1,3-thiazine-4-carboxylic acid).

4,5,9,10-tetrahydro-4-methyl-2-phenyl-9,10-epoxy-3H,10aH-cyclobuta[a]benzo[2,3,4-de]isoquinoline-3,5-dione.

In the title compound, C(21)H(15)NO(3), which is one of the photoreaction products of N-methyl-1,8-naphthalenedicarboximide with phenylacetylene, the cyclobutene and epoxy rings are trans to each other across the cyclohexene ring of the tetralin moiety. The dihedral angle between the mean planes of the cyclobutene and cyclohexene rings is 112.80 (2) degrees, while the latter makes a dihedral an...

14-Methoxy-2,16-dioxapentacyclo[7.7.5.01,21.03,8.010,15]henicosa-3(8),10,12,14-tetraene-7,20-dione

The title compound, C(20)H(20)O(5), was synthesized from the reaction between 3-methoxysalicaldehyde and 1,3-cyclo-hexa-nedione in the presence of palladium(II) chloride. The two fused xanthene rings and one of the six-membered cyclo-hexane rings adopt envelope conformations, while the other six-membered cyclo-hexane ring is in a chair conformation. The mol-ecular packing is stabilized by weak ...